This paper develops a new automatic and location-adaptive procedure for estimating regression in a Functional Single-Index Model (FSIM). This procedure is based on $k$-Nearest Neighbours ($k$NN) ideas. The asymptotic study includes results for automatically data-driven selected number of neighbours, making the procedure directly usable in practice. The local feature of the $k$NN approach insures higher predictive power compared with usual kernel estimates, as illustrated in some finite sample analysis. As by-product, we state as preliminary tools some new uniform asymptotic results for kernel estimates in the FSIM model.